Frequently, hsp leads to abdominal pain and intestinal bleeding, renal involvement and joint pain. The disease is characterized by abnormal deposits of immunoglobulin a an antibody in the blood vessels, leading to their inflammation vasculitis. Pdf henochschonlein purpura is the most common vasculitis in children. Health professionals diagnosis henochschonlein purpura through blood tests elevated iga. Schonleinhenoch purpura hsp is a systemic vasculitis that affects vessels of a small calibre. Henochschonlein purpura hsp is a shortterm inflammation of certain blood vessels vasculitis thought to be triggered by a malfunction of the immune system. Interventions for preventing and treating kidney disease in henoch schonlein. Henochschonlein purpura is a childhood vasculitis that. Henochschonlein purpura also known as anaphylactoid purpura is a type of vasculitis that affects small blood vessels and characterized by elevated immunoglobulin a iga. When the blood vessels bleed, you get a rash called purpura. Henochschonlein purpura, leucocitoclastic vasculitis. Symptoms of this disease include skin lesions, joint pain, blood in urine hematuria, and abdominal pain. Pigmented purpuric dermatosis are distinguished from other purpura by size 0. Hemorrhagic macules, papules, and urticarial lesions on the foot of a child.
When blood vessels get inflamed, they can bleed into the skin, causing a reddishpurple rash purpura. Symptoms include a purple spotted skin rash, abdominal pain and gastrointestinal upsets such as diarrhoea. Iga vasculitis is caused by an abnormal response of the immune system. Gastrointestinal manifestations of henochschonlein purpura. It is characterized by a purpuric rash, painful swollen joints, and abdominal pain with vomiting.
Last week i went to the doctor with a rash on my lower legs. Henochschonlein purpura definition of henochschonlein. Iga vasculitis is a disease that involves purple spots on the skin, joint pain, gastrointestinal problems, and glomerulonephritis a type of kidney disorder. Clinical course of extrarenal symptoms in henochschonlein purpura. They did a quick blood test and said platelet level were normal and that and they did a urinalysis and said there was no protein. Gastrointestinal tract, henochschonlein purpura, renal involvement, vasculitis. Hematologic and immunological characteristics of henoch. Hsp can affect blood vessels in the bowel and the kidneys, as well. Symptoms and signs include a purpuric skin rash which comprises small spots and larger bruises, abdominal pain, gastrointestinal bleeding, joint pain and swelling, facial swelling and evidence of kidney disease with blood and protein in. The most striking feature of henoch schonlein purpura is a purplish rash, typically on the lower legs and buttocks. This page includes the following topics and synonyms. It is not clear what triggers the condition, but it often appears a few weeks after an upper respiratory infection such as strep or mycoplasma. N e u m o n i a s intersticiales y, mas grave, hemorragia pulmo nar.
Symptoms can begin in children, most commonly between the ages of 4 and 7 years, soon after an upper respiratory tract infection or a streptococcalpharyngitis sore throat infection. The iga deposits in vessel walls, associated with the. Hsp is most common in younger pts clinical red maculopapules on. The result is inflammation in the microscopic blood vessels in. Henochschonlein purpura hsp is an immunologically mediated disease associating purpura plus urticaria, characteristically affecting lower limbs, buttocks, and elbows.
Henochschonlein purpura hsp, also called immunoglobulin a vasculitis igav, is a vascular disease that primarily affects small blood vessels. The small vessels of the skin, joints, kidneys, and digestive organs. Children particularly boys are most commonly affected, although the. Henochschonlein purpura, henoch schonlein purpura, henochschoenlein purpura, henoch schoenlein purpura, hsp, iga vasculitis, immunoglobulin a vasculitis. Please use one of the following formats to cite this article in your essay, paper or report. Background 1st described in 1801 by william heberden, a physician in london, who wrote about a case of a 5 year old boy with hematuria, abdominal pain. Henochschonlein purpura, sometimes known as hsp, is an autoimmune condition that causes inflammation in the tiny blood vessels of the skin. In describing hsp, heberden wrote of a 5year old boy who was seized with pains and swellings in various partshe sometimes had pains in his belly with vomitingand the urine was tinged with blood.
953 1513 1098 1484 810 10 18 1316 1317 1121 1644 1031 1027 780 662 480 1569 1477 172 1111 705 1041 486 1538 1576 1145 88 170 756 1402 899 1076 1392 1349 269 575